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Chloroquine is a drug from the group of 4-aminoquinoline derivatives. Chloroquine has been used to treat malaria in regions where it remains sensitive to the drug. It is also sometimes used to treat amebiasis, rheumatoid arthritis, and systemic lupus erythematosus. You can order Chloroquine in our pharmacy right now.
Chloroquine analogs have been known since the 17th century. So the people of Peru mined the bark of the cinchona tree and used its extract to fight chills and fever. In 1633, this medicine became available in Europe. In the 19th century, the active ingredient quinine, the first quinoline antimalarial drug, was isolated from the cinchona bark extract. Its analogue — Chloroquine — was isolated in 1934 and in 1947 it was introduced into practice for the prevention of malaria.
How does Chloroquine work?
It inhibits the synthesis of nucleic acids in cells and has a moderate immunosuppressive, specific and nonspecific anti-inflammatory effect. As an antimalarial, it works against the asexual form of the malaria parasite in the stage of its life cycle within the red blood cell.
Chloroquine mildly suppresses the immune system, so it is also used to treat systemic autoimmune diseases such as rheumatoid arthritis and lupus erythematosus, although the mechanism of action in these cases is still unclear. From 2020 the mechanism of action of chloroquine in the treatment of patients with COVID-19 is also being studied.
How to use Chloroquine?
Chloroquine is available in pill form and it is meant to be administered orally. Before ordering chloroquine in our pharmacy, you should clarify specific dosage and treatment regimen with your attending physician.
What contraindications Chloroquine has?
Chloroquine has a number of contraindications, such as retinopathy, keratopathy, visual impairment, and hypersensitivity to chloroquine. Please check all the possible contraindications before ordering chloroquine in our pharmacy.
Due to its high toxicity, Chloroquine also has a fairly large number of side effects such as blurred vision, nausea, vomiting, abdominal cramps, headache, diarrhea, leg swelling, shortness of breath, muscle weakness, easy bruising and bleeding, and mental problems.
When taking chloroquine, the dosage of the drug should also be strictly observed, exceeding it can lead to serious heart problems: ventricular fibrillation and a drop in blood pressure, and also to seizures, changes in vision and even respiratory arrest.
Chloroquine is an effective treatment for malaria with proven effectiveness. At the same time, due to its high toxicity, the drug should be taken strictly in accordance with the instructions of your attending physician.
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